Solving for Why

Dr. Mark Shrime is one of the most remarkable humans I’ve ever met. I knew he’d write a wonderful book—I just didn’t expect to dog ear every page and underline so many wonderful thoughts that he puts so well onto the page. ―Dana Perino, New York Times bestselling author of Everything Will Be Okay

Following a traumatic car accident, Mark Shrime—the child of Lebanese immigrants fleeing a civil war, who later became a successful practicing surgeon in Boston—found himself compelled to change the course of his life, determined to find meaning and satisfaction even if it meant diverting from America’s idea of “success.” Featuring stories, insights, and research from his own exceptional life and work, Solving for Why is the story of Dr. Shrime's search for—and discovery of—lifelong fulfillment.


Professor Mark G. Shrime, MD, MPH, PhD, FACS, is the International Chief Medical Officer at Mercy Ships and a Lecturer in Global Health and Social Medicine at the Harvard Medical School.

He previously served as the O’Brien Chair of Global Surgery at the Royal College of Surgeons in Ireland, as the founder and Director of the Center for Global Surgery Evaluation at the Massachusetts Eye and Ear Infirmary, and as Research Director for the Program in Global Surgery and Social Change at Harvard. 

He is the author of seminal papers on the global burden of surgical disease, the financial burden facing surgical patients, and the number of people who cannot access safe surgery worldwide. He served as a co-author on the Lancet Commission on Global Surgery.

Dr. Shrime graduated summa cum laude from Princeton University in 1996 with a BA in molecular biology. He received his MD from the University of Texas in 2001, after taking a year to teach organic chemistry in Singapore. Medical school was followed by a residency in otolaryngology at the joint Columbia/Cornell program in Manhattan, followed, in turn, by a fellowship in head and neck surgical oncology at the University of Toronto in 2007. He completed a second fellowship in microvascular reconstructive surgery, also at the University of Toronto, in 2008. He was the first to identify a novel independent prognostic indicator in head and neck cancer.

To date, he has worked and taught in Liberia, Sierra Leone, Guinea, Benin, Togo, Congo, Haiti, Saudi Arabia, Cameroon, and Madagascar. In May, 2011, he graduated with an MPH in global health from the Harvard School of Public Health, where he was a finalist for both the Albert Schweitzer award and the HSPH Student Recognition award, and in May, 2015, he received his PhD in health policy from Harvard University, with a concentration in decision science.

His research has been supported by the National Institutes of Health, the Iris O’Brien Foundation, the Damon Runyon Cancer Foundation, an anonymous donation to the Center for Global Surgery Evaluation, the GE Foundation’s Safe Surgery 2020 project and the Steven C. and Carmella Kletjian Foundation.

His academic pursuits focus on patient decision-making and surgical delivery in low- and middle-income countries, where he has a specific interest in the intersection of health, impoverishment, inequity, and global development. His work aims to determine optimal policies and platforms for surgical delivery that maximize health benefits while simultaneously minimizing the risk of financial catastrophe faced by patients. In 2018, he was awarded the Arnold P. Gold Humanism in Medicine Award by the American Academy of Otolaryngology—Head and Neck Surgery.

When not working, he is a photographer, public speaker, and rock climber and has competed on Seasons 8, 9, and 11 of American Ninja Warrior.